Acne nod­ules are hard, pus-filled lesions that occur under the skin. Also referred to as cys­tic acne, acne nod­ules do not respond to com­mon acne med­ica­tions such as ben­zoyl per­ox­ide and sal­i­cylic acid. More­over, due to the fact that acne nod­ules occur deep inside the der­mis they must be...
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